Shaun Deeb 100k to 1M 17% body fat bet with Bill Perkins
This is going to be tough!!!!!!!!!
That's not how appetite is controlled. Semaglutide works by slowing the movement of food through the stomach, which in turn makes people feel more full having eaten less food than they normally would. There is a gut-brain communication system responsible for this. As for caloric set point and satiety, think of them as being akin to thermostats. A comfortable temperature set
The point is the thermostat is not "broken" by default. Its broken because these people, with their behavior over time, have rerouted their systems so they now lean towards overeating. Its not an actual biologicaly based disease when its entirely their own fault that their bodies are the way they are.
Its akin to me saying I have a disease because my VO2 max is crap, when the main factor by far is me not doing any endurance workouts for the last decade. And now the world has to cater to my bad endurance because I have a disease.
I am a blind man, not because I was born blind or was blinded during life, but because I refuse to open my eyes
Can somebody please cure my disease?
And dont blind-shame me by telling to open my eyes like its as easy as laying off the junkfood
The point is the thermostat is not "broken" by default. Its broken because these people, with their behavior over time, have rerouted their systems so they now lean towards overeating. Its not an actual biologicaly based disease when its entirely their own fault that their bodies are the way they are.Its akin to me saying I have a disease because my VO2 max is crap, when the ma
Spot on, except for all the facts of the underlying biology and pathophysiology that were taken into account starting 80 years ago with the designation of morbid obesity as a disease, and continuing to today.
Thirst is also a biologically tightly regulated and related process. It, too, has a well understood underlying biology, and there are a family of disorders of it as well.
Spot on, except for all the facts of the underlying biology and pathophysiology that were taken into account starting 80 years ago with the designation of morbid obesity as a disease, and continuing to today.
Thirst is also a biologically tightly regulated and related process. It, too, has a well understood underlying biology, and there are a family of disorders of it as well.
*Tuba noises*
I think the important distinction here is that for the vast majority of presently obese people, they were not born with a broken internal thermostat. They stuffed their body with junk food until it broke their thermostat.
And yes, for those in lower socioeconomic classes, there are a number of environmental factors that contribute. Such as decreased access to fresh produce and quality meat, more access to processed fast food, less access to health care, less access to green spaces, less access to health education. But these people were not born destined to be fat based on their biological makeup.
Genetics of Obesity: What We Have Learned Over Decades of Research
The point is the thermostat is not "broken" by default. Its broken because these people, with their behavior over time, have rerouted their systems so they now lean towards overeating. Its not an actual biologicaly based disease when its entirely their own fault that their bodies are the way they are.Its akin to me saying I have a disease because my VO2 max is crap, when the ma
Countdown to you invoking the law of thermodynamics.
If you think the world caters to overweight people, you are pretty clueless.
I mean maybe not the world but doesnt USA cater to overweight people?
They can practice their hobby (eating copious amounts of unhealthy foods) almost anywhere
Genetics of Obesity: What We Have Learned Over Decades of Research
"it is not known whether these larger effect sizes precede obesity or are caused by an obese state."
This line basically invalidates the premise.
"it is not known whether these larger effect sizes precede obesity or are caused by an obese state."
This line basically invalidates the premise.
Not hardly. The genes identified as being linked to morbid obesity syndromes sometimes are monogenic (i.e., present at birth and driven by mutation in a single gene) or polygenic (i.e., present at birth and one of a collection of gene defects driving morbid obesity. You cherrypicked a single reference to an example of one of the large effect linkages from which cause and effect relationships are incompletely worked out.
Perhaps the geneticists trained and experienced in the field and studying genes tied to obesity understand the issues, limitations, and interpretations better than you.
For example, the leptin involvement in obesity is well established, the underlying cellular and physiological connections with weight disregulation well understood, and the science backed by hundreds of studies conducted over a significant period of time, using a diversity of methods and approaches, and convergent on the involvement. It establishes that leptin resistance is an acquired state, is controlled by many factors and not overeating alone, and that contributes to dysregulation of the signaling between fat tissue and regions of the brain that control appetite.
Correlation is not causation. How many people who aren't morbildy obese have those same genes? Maybe it's the gene that makes a person insufferable to be around, and the obesity is just a coping mechanism for them.
Correlation is not causation. How many people who aren't morbildy obese have those same genes? Maybe it's the gene that makes a person insufferable to be around, and the obesity is just a coping mechanism for them.
And 'causation' is causation:
Leptin is a hormone your body releases that helps it maintain your normal weight on a long-term basis. The level of leptin in your blood is directly related to how much body fat you have. Leptin resistance causes you to feel hungry and eat more even though your body has enough fat stores.
Feeling hungry is one thing
Stuffing your stomach full of KFC, McDonalds and Burger King is another.
Its still a choice. They could satisfy their hunger with healthier foods or just have the discipline to not always eat when hungry.
But they make a totally different choice. So I dont see them as victims and certainly not as people with a disease, no matter if they are Leptin resistant or not.
Not hardly. The genes identified as being linked to morbid obesity syndromes sometimes are monogenic (i.e., present at birth and driven by mutation in a single gene) or polygenic (i.e., present at birth and one of a collection of gene defects driving morbid obesity. You cherrypicked a single reference to an example of one of the large effect linkages from which cause and effe
It's all ABSTRACT. It's all just a guess without any actual science, which I'm fine with but that line that I quoted is the answer. Neural pathways are developed and strengthened in the brain. Fat people not feeling satiated is from years of chronic abuse like a drug addict not getting the same high as their first time. Neither of those are diseases. Addiction is not a disease, it's a choice. Morbid obesity is not caused by disease it's caused by choices. Going down that path alters brain chemistry such that it becomes harder to resist.
Deeb was denied his ninth bracelet, but took second for around $160K in the $3K nine game mix. That should help his Series ledger.
It's all ABSTRACT. It's all just a guess without any actual science, which I'm fine with but that line that I quoted is the answer. Neural pathways are developed and strengthened in the brain. Fat people not feeling satiated is from years of chronic abuse like a drug addict not getting the same high as their first time. Neither of those are diseases. Addiction is not a dis
In truth, it's all science without any guessing, unlike your take which is backed only by the fact that you thought of it and so it must be true. The two links, one from a published scientific review of leptin that details some of the genetic, molecular, cellular, and physiological mechanisms underlying morbid obesity, and the second the synopsis of the science of obesity from the Cleveland Clinic, one of Americas best and most renowned biomedical research and treatment institutes, give a taste of the scientific understanding of the disorder. The backing by the World Health Organization and the American Medical Association dating back 80-some years on morbid obesity as a disease seals the deal.
Here's a link to the world's archive of peer reviewed, vetted scientific journal publications, PubMed, run by the US National Library of Medicine. Anyone can type in keywords and get lists of published studies on any topic relevant to biomedicine. It's a great way to become informed:
So what happens if a morbidly obese person starts eating healthy and nothing more than necessary?
Would he remain as morbidly obese because he has a disease? No right
If someone holds both the cure and the cause of a "disease" but chooses a lifestyle that creates/retains that "disease" instead of one that cures it and stops him from being a drain on society I dont regard them as diseased whatsoever.
I am saying its an easy choice to make or conform to (certainly after years of eating unhealhty) but its a choice nonetheless.
namisgr77, do serial rapists have a disease? Their desire to rape has biological component certainly.
If you don't believe so, what's the difference between a morbidly obese person choosing to eat more calories than they need and a serial rapist choosing to rape?
Why is one a disease and not the other?
Thank you.
Countdown to you invoking the law of thermodynamics.
If you think the world caters to overweight people, you are pretty clueless.
Implying the law of thermodynamics doesnt apply to fat people.. lol. Fat people want to be catered to, thats what the entire goal of the "obesity is a disease" movement. To get special treatment for their poor life choices.
Like the obese moron who tried to sue Lyft because she didnt fit into a cab, or the people advocating for fat people getting 2 air plane seats for the price of one becasue they have a disability.
It has obv nothing to do with a disease lmao what are you guys even discussing here.
But once u are attracted to sugar and unhealthy food in general its very hard to break that habbit. Especially with kids and family around you most of the time and a stressful job like Poker. If you are also into weed then its even more difficult. But disease? Just nope.
The world needs more fat shaming, not less. It's not about beauty. These morbidly obese people are slowly killing themselves, not to mention being a relentless drain on society's healthcare resources.
Im not for fat shaming, but
The women who are always trying to (fakely) prop up their homegirl who's fat-thats a problem. A dude, who's a good friend, would belike "get your fatass in the gym". Nobody should be told they look good when theyre obese or >25lbs over weight. If theyre working on getting healthier they deserve all the support they need.
For those of you who live on the west coast or like south Florida/new york/another country....come to the Midwest or south in America. **** is bad.
Im not for fat shaming, butThe women who are always trying to (fakely) prop up their homegirl who's fat-thats a problem. A dude, who's a good friend, would belike "get your fatass in the gym". Nobody should be told they look good when theyre obese or >25lbs over weight. If theyre working on getting healthier they deserve all the support they need. For those of you who live on
This is true.
I remember years back Kate Moss waffling on about some massively obese singer (Beth Ditto) and saying "i think she looks great, i love her shape". Which v v clearly was absolute bullshit, and does absolutely nothing to assist the obese get better. Its a v v common thing with females weirdly as like you say, a male would just say "get to gym fatso you look like youre about to have a heart attack ffs"
It's all ABSTRACT. It's all just a guess without any actual science, which I'm fine with but that line that I quoted is the answer. Neural pathways are developed and strengthened in the brain. Fat people not feeling satiated is from years of chronic abuse like a drug addict not getting the same high as their first time. Neither of those are diseases. Addiction is not a dis
Sorry buddy, but youre very ignorant.
You need to study up on these things you seem to be talking out your ass about.
namisgr77, do serial rapists have a disease? Their desire to rape has biological component certainly.
If you don't believe so, what's the difference between a morbidly obese person choosing to eat more calories than they need and a serial rapist choosing to rape?
Why is one a disease and not the other?
Thank you.
This is 100% the direction they are going with all of this.
Considering morbid obesity has been classified as a disease for nearly 80 years, and never re-classified as anything but in all the intervening time and after all the research both preclinical and clinical, you should certainly be able to show us what direction "they" went with it.
